THERMUCNA
THERMUCNA
THERMUCNA
Thermoresponsive and mucoadhesive nanogels for antimicrobial delivery
THERMUCNA is a project funded by the European Union’s Horizon 2020 research and innovation program under grant agreement No 896775, and it is devoted to the development of nanomaterials towards the new generation of therapeutics to target antimicrobial infections. Specifically, this project is focused on developing nanoformulations to prevent and treat bacterial infections in dairy cows. The possibility to reduce antibiotic use in producer animals significantly contributes to reducing bacterial resistance development.
About Us
THERMUCNA is a project funded by the EU in the framework of an individual Marie Skłodowska-Curie fellow, obtained by the Dra Maria Soledad Orellano and supervised by Dr. Marcelo Calderón.
About Dra. Maria Soledad Orellano
Soledad received her Bachelor Degree in Chemistry from the National University of Rio Cuarto (Argentina). In 2014 she obtained a Ph.D. fellowship funded by the Argentinean National Council of Scientific and Technical Research (CONICET). She worked on the synthesis of chitosan nanoparticles and their therapeutic effect against bovine mastitis pathogens and their interaction with bovine cells in vitro as well. Her thesis work was performed at the National University of Villa Maria (Argentina) under the supervision of Prof. Carina Porporatto and Prof. R. Dario Falcone. She received her Ph.D. degree in 2019 from the National University of Rio Cuarto (UNRC, Argentina).
In 2018 she obtained a Fulbright grant to carry out an internship for three months at the University of Tennessee, Knoxville, United States under the supervision of Prof. Raul A. Almeida. She worked on the antimicrobial activity of chitosan nanoparticles against intracellular Staphylococcus aureus using in vitro mammary gland model.
In 2019 she obtained a postdoctoral fellowship funded by CONICET to perform postdoctoral training at UNRC (Argentina) under the supervision of Prof. N. Mariano Correa. She worked on the synthesis of chitosan-based polymeric surfactants and the physicochemical characterization of polymeric micelles using fluorescence molecular probes.
Since March 2021 she joined the Responsive Polymer Therapeutics Group in the framework of a Marie Skłodowska-Curie individual fellowship.
About Responsive Polymer Therapeutics Group
RPT group combines the interests and expertise of researchers working at the interface between polymers and biology. A great effort is given to fine-tune the functionality of polymeric materials through the control of synthetic parameters and the incorporation of responsive modalities. Encapsulation, decoration, entrapment, and conjugation of biologically active moieties are explored in order to achieve a broad spectrum of applications. Please, visit our group website to get more information.
Publications
Orellano, M. S., Sanz, O., Camarero-Espinosa, S., Beloqui, A., & Calderón, M. (2022). Nanomedicine, 17(4), 197-200
CONTÁCTANOS
Paseo Manuel Lardizabal, 3, 20018 Donostia, Gipuzkoa, España
+34943015325